MAPK14 anticorps

N° du produit ABIN7116420

Cet anticorps anti-MAPK14 est un anticorps Souris Monoclonal détectant MAPK14 dans WB, IHC et ELISA. Adapté pour Humain et Porc.

Aperçu rapide pour MAPK14 anticorps (ABIN7116420)

Antigène: MAPK14 (Mitogen-Activated Protein Kinase 14 (MAPK14))

Reactivité: Humain, Porc

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MAPK14 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: 6D2

Détail du produit anti-MAPK14 anticorps

Fonction: MAPK14 antibody

Purification: Protein A+G purification

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: mitogen-activated protein kinase 14

Isotype: IgG1

Information d'application

Indications d'application: WB: 1:1000-1:4000, IHC: 1:100-1:400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur MAPK14

Antigène: MAPK14 (Mitogen-Activated Protein Kinase 14 (MAPK14))

Autre désignation: MAPK14

Sujet:

Synonyms: Mitogen-activated protein kinase 14 (MAP kinase 14, MAPK 14)|Cytokine suppressive anti-inflammatory drug-binding protein (CSAID-binding protein, CSBP)|MAP kinase MXI2|MAX-interacting protein 2|Mitogen-activated protein kinase p38 alpha (MAP kinase p38 alpha)|Stress-activated protein kinase 2a (SAPK2a)|MAPK14|CSBP|CSBP1|CSBP2|CSPB1|MXI2|SAPK2A

Background: MAPK14 (mitogen-activated protein kinase 14) is also named as SAPK2A, p38MAPK, CSBP1, RK, p38, EXIP, Mxi2, CSBP2, PRKM14, PRKM15, CSPB1, p38ALPHA and belongs to the MAP kinase subfamily. MAPK14-signaling is a central pathway for the integration of instructive signals in dendritic cells for T(H)17 differentiation and inflammation(PMID:22231518). It plays an important role in the regulation of hematopoietic stem cellself-renewal in vitro and inhibition of MAPK14 activation with a small molecule inhibitor may represent a novel approach to promote ex vivo expansion of hematopoietic stem cell(PMID:21198398). This protein has 4 isoforms produced by alternative splicing.

Poids moléculaire: 38 kDa

ID gène: 1432

UniProt: Q16539

Pathways: Signalisation MAPK, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Hepatitis C, Toll-Like Receptors Cascades, Autophagy, Thromboxane A2 Receptor Signaling, BCR Signaling, S100 Proteins